Welcome to the Holiday Inn Poplar Bluff, conveniently located off U.S. 60 and Business 67 on Westwood Blvd. Our hotel is the ideal choice for business near area corporations such as Briggs & Stratton, Gates Rubber, Nortek, Mid Continent Nail, Empire Comfort Systems, Poplar Bluff Regional Medical Center, and John J. Pershing VA Medical Center. Enjoy many attractions and events at Current River, Lake Wappappello, Mark Twain National Forest, Black River Coliseum, and The Historical Museum of Poplar Bluff. The Holiday Inn Poplar Bluff offers recently renovated guestrooms that feature a beautiful color scheme and comfortable design. Guest will enjoy hotel complimentary amenities, such as free Wi-Fi, Business Center, state of the art Fitness Center, and indoor pool. Hold your large or small event with us in our ballroom or boardroom. Book with us and experience hospitality at its finest!