The Moorhead campus of Globe University/Minnesota School of Business (GU/MSB) is near the intersection of Interstate Highway 94 and 34th Street, across the street from Menards on the east side of town.

The two-story, 30,000-square-foot facility, built in 2008, is designed for hands-on training, and includes a fully equipped veterinary suite, a massage lab, library, tutoring services, student lounge and classrooms. The campus provides students with a warm, welcoming place to study, attend class or catch up with friends.

For several years before the opening of the Fargo-Moorhead campus, Globe University/Minnesota School of Business operated the Fargo, North Dakota, Student Resource Center, a facility where GU/MSB students taking online classes could work in a coffeehouse atmosphere and receive staff support. Today online or online/on-campus students receive those same services at the Moorhead campus.